DNA Health
The DNA Health test helps you take a personalised approach to your health by looking at how your genes influence the way your body uses nutrients. With this information, we can tailor your diet, lifestyle, and supplements to support your long-term wellbeing and reduce your risk of disease.
Your genes play a big role in how well your body absorbs and uses vitamins and minerals — and how your cells repair damage, clear toxins, and protect against disease. This test identifies specific gene variations that may affect those processes, allowing us to recommend targeted nutrition and lifestyle changes to support healthy ageing and prevent chronic illness.
Many current dietary guidelines are designed to prevent deficiencies — but this test goes a step further by helping define your optimal needs for key nutrients based on your unique genetic profile.
It’s especially useful if you want to:
Understand your risk of chronic lifestyle-related conditions
Optimise your energy, immunity, and long-term health
Take a proactive approach to healthy ageing
Personalise your supplement and diet plan
SAMPLE TYPE: BLOOD SPOT
The DNA Health test helps you take a personalised approach to your health by looking at how your genes influence the way your body uses nutrients. With this information, we can tailor your diet, lifestyle, and supplements to support your long-term wellbeing and reduce your risk of disease.
Your genes play a big role in how well your body absorbs and uses vitamins and minerals — and how your cells repair damage, clear toxins, and protect against disease. This test identifies specific gene variations that may affect those processes, allowing us to recommend targeted nutrition and lifestyle changes to support healthy ageing and prevent chronic illness.
Many current dietary guidelines are designed to prevent deficiencies — but this test goes a step further by helping define your optimal needs for key nutrients based on your unique genetic profile.
It’s especially useful if you want to:
Understand your risk of chronic lifestyle-related conditions
Optimise your energy, immunity, and long-term health
Take a proactive approach to healthy ageing
Personalise your supplement and diet plan
SAMPLE TYPE: BLOOD SPOT
The DNA Health test helps you take a personalised approach to your health by looking at how your genes influence the way your body uses nutrients. With this information, we can tailor your diet, lifestyle, and supplements to support your long-term wellbeing and reduce your risk of disease.
Your genes play a big role in how well your body absorbs and uses vitamins and minerals — and how your cells repair damage, clear toxins, and protect against disease. This test identifies specific gene variations that may affect those processes, allowing us to recommend targeted nutrition and lifestyle changes to support healthy ageing and prevent chronic illness.
Many current dietary guidelines are designed to prevent deficiencies — but this test goes a step further by helping define your optimal needs for key nutrients based on your unique genetic profile.
It’s especially useful if you want to:
Understand your risk of chronic lifestyle-related conditions
Optimise your energy, immunity, and long-term health
Take a proactive approach to healthy ageing
Personalise your supplement and diet plan
SAMPLE TYPE: BLOOD SPOT
Tests for:
Gene variations associated with metabolic and biological processes
Analytes measured:
Lipid Metabolism
LPL: Removes lipids from the circulation by hydrolysing triglycerides into free fatty acids.
CETP: Plays a key role in the metabolism of HDL and mediates the exchange of lipids between lipoproteins.
APOC3: Plays an important role in cholesterol metabolism.
APOE: Is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Affects antioxidant requirement.
B Vitamins/Methylation
MTHFR: Directs folate from the diet either to DNA synthesis or homocysteine re-methylation.
MTR: Catalyses the re-methylation of homocysteine to methionine.
COMT: Catalyses the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine.
MTRR: Catalyses methylcobalamin, which is essential for maintaining adequate intracellular pools of methionine. It is also responsible for maintaining homocysteine concentrations at non-toxic levels.
CBS: Catalyses the conversion of homocysteine to cystathionine and is directly involved in the removal of homocysteine from the methionine cycle.
Detoxification
CYP1A1: The cytochrome P450 enzyme converts environmental pro-carcinogens to reactive intermediates, which are carcinogenic.
GSTM1: Influences Phase II detoxification. It is responsible for the removal of xenobiotics, carcinogens, and products of oxidative stress.
GSTP1: Influences the metabolism of many carcinogenic compounds.
GSTT1: A member of a super family of proteins that catalyses the conjugation of reduced glutathione.
NQO1: Quinone Reductase is primarily involved in the detoxification of potentially mutagenic and carcinogenic quinones derived from tobacco smoke, diet and oestrogen metabolism.
Inflammation
IL-6: Plays a crucial role in inflammation by regulating the expression of C reactive protein (CRP).
TNF-A: TNFa is a pro-inflammatory cytokine, secreted by both macrophages and adipocytes, which has been shown to alter whole body glucose homeostasis, and has been implicated in the development of obesity, obesity-related insulin resistance and dyslipidemia.
Food Responsiveness and Sensitivity
MCM6: Associated with adult hypolactasia.
FADS1: Influences blood fat concentrations by affecting desaturase enzyme efficiency.
CYP1A2: This detoxification enzyme influences the ability to metabolise caffeine.
ACE & AGT: Part of the renin-angiotensin system and response to salt.
HLA DQ2/DQ8: Major genetic predisposition for coeliac disease
Vitamin Metabolism
BC01: Catalysing carotenoids to retinal (vitamin A)
CYP2R1: Conversion of vitamin D to 25(OH)D
FUT2: Vitamin B12 absorption and transport
GSTT1: Contributing to glutathione-ascorbic acid (vitamin C) antioxidant cycle
Iron Overload
HFE: Regulates iron absorption by regulating the interaction of the transferring receptor with transferrin. Hereditary haemochromatosis results from defects in the HFE gene.
Oxidative Stress
eNOS: Influences vascular tone and peripheral vascular resistance. It also has vaso-protective effects by suppressing platelet aggregation, leukocyte adhesion and smooth muscle cell proliferation.
MnSOD/SOD2: Has vital anti-oxidant activity within the cell, especially within the mitochondria. It destroys the radicals that are normally produced within cells.
Bone Health
VDR: Has a profound influence on bone density.
COL1A1: Influences the ratio of collagen-alpha chains produced by bone cells, affecting bone mineralisation of bone and bone strength.
Insulin Sensitivity
PPARG: Involved in adipocyte differentiation. It is a transcription factor activated by fatty acids, and is also involved in the regulation of glucose and lipid metabolism.
TCF7L2: Influences blood glucose homeostasis – both insulin secretion and resistance.
FTO: Influences susceptibility to obesity and risk for type 2 diabetes.
SLC2A2: Facilitates glucose induced insulin secretion and is involved in food intake and regulation.